How to assess the implications of changing temperature regimes under which chemical reactions are carried out is the focus of a white paper from Mettler Toledo. Understanding temperature change and the energy accumulation associated by the reaction are critical to chemical process safety, the company notes. The white paper discusses how to assess the implications of changing temperature regimes under which chemical reactions are carried out.  Examples from both the laboratory and pilot plant are used to answer the following questions:

• Why and when does the thermal accumulation occur?
• Why is energy accumulation important to consider, and how big is it?
• What is the impact of an incorrect calculation of accumulation?

The white paper was written for chemists and chemical engineers working in process development and scaleup in the pharmaceutical and chemical industries. Download it by visiting http://bit.ly/2j5XERF.